Mix ground meat, egg, Worcestershire, and ketchup in a large bowl. Add crackers and seasonings to the wet mixture; mix thoroughly.

Preheat oven to 400°F. Press meat mixture evenly into a medium casserole dish. Spread ketchup over the entire surface.

Cover tightly with foil; bake approximately 1 hour in preheated oven, checking for an internal temperature of 160°F for ground beef or pork.

Check carefully after about 30 minutes; the loaf may shrink and release grease. If grease is excessive, carefully remove dish and rest briefly before handling. Cool grease and discard in trash, never down the sink, even with hot water.

Once fully cooked, rest a few minutes before slicing. Serve with preferred sides, such as roasted potatoes and pinto beans.